A Good Omen
A Good Omen Podcast
Learning Pearls with Daniel Lim (#1)
0:00
-44:27

Learning Pearls with Daniel Lim (#1)

Physician Disputes, Syncope Workup, Gallbladder Pain, & D-Dimer shenanigans

I’m experimenting with a new format in between typical interviews where my good friend Daniel and I share some learning points we have picked up in the past few months from our reading and clinical experiences. Let us know how you like this format in the comments

[2:00] Joshua’s approach to learning from physician disputes (evidentiary standards vs therapeutic fashion vs differing clinical contexts vs differing psychological propensities of the clinician vs patient values)

[13:00] Daniel’s improved approach to syncope workup

https://jamanetwork.com/journals/jama/article-abstract/2736568?utm_source=openevidence&utm_medium=referral

https://pmc.ncbi.nlm.nih.gov/articles/PMC10024337/

https://www.coreimpodcast.com/2025/09/11/orthostasis-part-1-gray-matters/

https://www.coreimpodcast.com/2025/09/22/orthostatic-hypotension-part-2-gray-matters/

[19:50] Joshua’s renewed focus on the importance of the history of science

  • Myth #1: Science is a game of lone intellectual heroes

  • Myth #2: Science is a clear systematic approach to understanding the world in practice

“Ask a scientist what he conceives the scientific method to be, and he will adopt an expression that is at once solemn and shifty-eyed: solemn because he feels he ought to declare an opinion; shifty-eyed because he is wondering how to conceal the fact that he has no opinion to declare.” Induction and Intuition in Scientific Thought (London: Methuen 1969) p. 11.

[25:30] Daniel’s improved illness script for gallbladder pain

https://jamaevidence.mhmedical.com/content.aspx?bookid=845&sectionid=61357499

https://clinicalproblemsolving.com/2020/02/09/clinical-reasoning-corner-likelihood-ratios/

[34:50] The new way Joshua will approach Continuous lab values (like D-dimer) with interval likelihood ratios rather than a simple +/- Likelihood Ratio

https://pubmed.ncbi.nlm.nih.gov/28370759/

Discussion about this episode

User's avatar

Ready for more?